Contactin-associated protein-like 3 (IPR028873)

Short name: CASPR3

Overlapping homologous superfamilies


Family relationships



The NCP family (for Neurexin-IV/Caspr/Paranodin) represents a distinct subgroup of the neurexins that includes mammalian Caspr (Contactin associated protein, also known as Paranodin), Caspr2, Caspr3, Caspr4 and Caspr5, and Drosophila Neurexin-IV. Both the neurexins and members of the NCP subgroup mediate cell-cell interactions. However, while the neurexins are thought to mediate the interactions between neurons, NCP proteins mediate neuron-glial interactions and in invertebrates, glial-glial contact [PMID: 11395000].

Caspr3 may have a role in cell recognition within the nervous system [PMID: 12093160].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.