Cyclin-G1 (IPR028860)

Short name: CCNG1

Overlapping homologous superfamilies


Family relationships

  • Cyclin (IPR039361)
    • Cyclin-G1 (IPR028860)


Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles, and regulate cyclin dependent kinases (CDKs) [PMID: 12910258].

Members of the cyclin-G subfamily of cyclins can associate with cdk5 and GAK. They also interact with the B' subclass of PP2A phosphatase and with Mdm2 and may regulate the p53-Mdm2 network [PMID: 12015958]. In humans and other mammals, there are two cyclin-G subtypes - cyclin-G1 and cyclin-G2. Their expression is linked to cancer progression [PMID: 12015958, PMID: 24297335].

This entry represents cyclin-G1.

GO terms

Biological Process

GO:0051726 regulation of cell cycle

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.