Family

Cyclin I (IPR028856)

Short name: Cyclin_I

Overlapping homologous superfamilies

None.

Family relationships

  • Cyclin (IPR039361)
    • Cyclin I (IPR028856)

Description

Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles, and regulate cyclin dependent kinases (CDKs) [PMID: 12910258].

This entry represents cyclin I, which contains a cyclin box motif and is involved in various biological processes, such as cell survival, angiogenesis, and cell differentiation [PMID: 23907122]. Cyclin I binds to and activates Cdk5, thereby preventing apoptosis in podocytes [PMID: 16847066]. It is involved in the regulation of cell cycle progression and is linked to cancer [PMID: 23907122, PMID: 22772062, PMID: 15754132].

GO terms

Biological Process

GO:0051726 regulation of cell cycle

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER