Nuclear receptor coactivator 3 (IPR028818)

Short name: NCOA3

Overlapping homologous superfamilies


Family relationships


Nuclear receptor coactivator 3 (NCOA3, also known as AIB1) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors [PMID: 10713439]. These receptors can function as molecular switches [PMID: 10713439].

NCOA3 is overexpressed in a fraction of breast cancers and has been linked to prognosis and tamoxifen resistance [PMID: 10823921, PMID: 23226788].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0030374 nuclear receptor transcription coactivator activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.