Angiopoietin-related protein 4 (IPR028793)

Short name: ANGPTL4

Overlapping homologous superfamilies


Family relationships



Angiopoietin-related protein 4 (ANGPTL4, also known as HFARP) functions as an antiangiogenic modulatory factor that is involved in various neoplastic diseases [PMID: 14583458]. It acts as an apoptosis survival factor for vascular endothelial cells, and may have a protective function on endothelial cells through an endocrine action in liver [PMID: 10698685].

GO terms

Biological Process

GO:0001525 angiogenesis
GO:0043066 negative regulation of apoptotic process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005615 extracellular space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.