Baculoviral IAP repeat-containing protein 1 (IPR028789)

Short name: Naip

Overlapping homologous superfamilies


Family relationships



Baculoviral IAP repeat-containing protein 1 or neuronal apoptosis inhibitory protein (NAIP) is an anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. NAIP contains three baculoviral IAP repeat (BIR) domains at the amino-terminal region and a ATP/GTP binding site [PMID: 11955612]. NAIP has been shown to inhibit apoptosis in neurons [PMID: 10886345] and in several mammalian cell lines [PMID: 20171302].

GO terms

Biological Process

GO:0043066 negative regulation of apoptotic process

Molecular Function

GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.