Sushi repeat-containing protein SRPX2 (IPR028768)

Short name: SRPX2

Family relationships



Sushi repeat-containing protein SRPX2 is a multifunctional protein that is involved in seizure disorders, angiogenesis and cellular adhesion [PMID: 22242148, PMID: 19667118]. It acts as a ligand for the urokinase plasminogen activator surface receptor [PMID: 18718938]. The overexpression of SRPX2 enhances cellular migration and adhesion in gastric cancer cells [PMID: 19065654]. Mutations in SRPX2 gene cause rolandic epilepsy with speech dyspraxia and mental retardation X-linked (RESDX) [PMID: 16497722].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.