Ubiquitin carboxyl-terminal hydrolase 10 (IPR028767)

Short name: USP10

Family relationships



Ubiquitin carboxyl-terminal hydrolase 10 (USP10) is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, BECN1, SNX3 and CFTR [PMID: 11439350]. It regulates the localisation and stability of p53 by de-ubiquitinatiing p53 [PMID: 20096447]. It is also implicated in vesicular transport and trafficking of membrane proteins [PMID: 19398555].

GO terms

Biological Process

GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0016579 protein deubiquitination

Molecular Function

GO:0004843 thiol-dependent ubiquitin-specific protease activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.