Family

Protein HEG (IPR028720)

Short name: HEG

Family relationships

None.

Description

Protein HEG (heart of glass) is a receptor component of the CCM (cerebral cavernous malformations) signaling pathway which is a crucial regulator of heart and vessel formation and integrity [PMID: 19151727]. It may act through the stabilisation of endothelial cell junctions [PMID: 14680629, PMID: 23007647].

GO terms

Biological Process

GO:0007043 cell-cell junction assembly
GO:0007507 heart development

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER