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Overview
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Pathways & interactions
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Structures
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Cross-references
Syntaxin-2 (IPR028671)
Short name: STX2
Overlapping homologous superfamilies
- SNARE (IPR010989)
Family relationships
None.
Description
Syntaxin-2 (STX2), also known as epimorphin, belongs to the syntaxin family, which is a group of the membrane integrated proteins participating in exocytosis. Syntaxins are associated with various intracellular membrane compartments and have been implicated in various physiological processes such as axonal growth and cell division [PMID: 18691641].
STX2 is essential for epithelial morphogenesis [PMID: 7957204]. It may mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm [PMID: 15774481].
GO terms
Biological Process
GO:0007340 acrosome reaction
GO:0030154 cell differentiation
Molecular Function
No terms assigned in this category.
Cellular Component
GO:0016021 integral component of membrane
Contributing signatures
- PTHR19957:SF36 (PTHR19957:SF36)