Syntaxin-2 (IPR028671)

Short name: STX2

Overlapping homologous superfamilies

Family relationships



Syntaxin-2 (STX2), also known as epimorphin, belongs to the syntaxin family, which is a group of the membrane integrated proteins participating in exocytosis. Syntaxins are associated with various intracellular membrane compartments and have been implicated in various physiological processes such as axonal growth and cell division [PMID: 18691641].

STX2 is essential for epithelial morphogenesis [PMID: 7957204]. It may mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm [PMID: 15774481].

GO terms

Biological Process

GO:0007340 acrosome reaction
GO:0030154 cell differentiation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.