Centriolin (IPR028640)

Short name: CEP110

Overlapping homologous superfamilies


Family relationships



Centriolin (also known as CEP110) localises to the maternal centriole and functions in both cytokinesis and cell cycle progression [PMID: 12732615]. During the late steps of cytokinesis, centriolin anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission [PMID: 16213214]. Centriolin also interacts with Hook2 protein, which may function as adaptors to link various organelle cargos to dynein and may functions in centrosome positioning [PMID: 17140400].

GO terms

Biological Process

GO:0051301 cell division
GO:0000278 mitotic cell cycle

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.