Alcohol dehydrogenase family, zinc-type, class-II subfamily (IPR028632)

Short name: Zinc_ADH_II

Overlapping homologous superfamilies

Family relationships



This entry represents the class-II subfamily of the zinc-containing alcohol dehydrogenase family (also known as class II alcohol dehydrogenase or ADH2) (EC: The human gene that encodes this protein is called ADH4. Most of the proteins in this subfamily are from mammals. They are involved in the reduction of benzoquinones [PMID: 10514444]. In humans, it is specifically expressed in liver [PMID: 10514444].

GO terms

Biological Process

GO:0006069 ethanol oxidation

Molecular Function

GO:0004024 alcohol dehydrogenase activity, zinc-dependent
GO:0035276 ethanol binding
GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.