Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 (IPR028592)

Short name: QTRTD1

Overlapping homologous superfamilies

Family relationships



Queuine tRNA-ribosyltransferase accessory subunit 2 (Qtrt2 or QTRTD1) interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. It exchanges queuine for the guanine at the wobble position of tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) [PMID: 19414587].

GO terms

Biological Process

GO:0006400 tRNA modification

Molecular Function

GO:0008479 queuine tRNA-ribosyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.