Adenylate kinase isoenzyme 1 (IPR028582)

Short name: AK1

Overlapping homologous superfamilies

Family relationships


Adenylate kinases (AKs) are nucleoside monophosphate kinases, which catalyse the phosphorylation of AMP by using ATP or GTP as phosphate donors.

In humans, nine different AK isoenzymes have been identified (AK1-9). This entry represents AK1. AK1 is the major cytosolic isoform and is present in all tissues with its highest expression levels in skeletal muscle, brain and erythrocytes [PMID: 23416111].

GO terms

Biological Process

GO:0009142 nucleoside triphosphate biosynthetic process

Molecular Function

GO:0005524 ATP binding
GO:0004017 adenylate kinase activity
GO:0004550 nucleoside diphosphate kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.