Stomatin-like protein 1 (IPR028517)

Short name: SLP1

Overlapping homologous superfamilies


Family relationships


Stomatin-like protein 1 (SLP1 or STOML1) is highly expressed in brain [PMID: 9931417]. SLP1 is a membrane protein with a characteristic bipartite structure containing a stomatin domain and a sterol carrier protein-2 (SCP-2) domain. It interacts with stomatin and is targeted to late endosomes, which suggests a role in sterol/lipid transfer and transport [PMID: 19696025]. SLP1 has been shown to interact with F-box protein Fbw7 [PMID: 23082202].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.