Family

Putative E3 ubiquitin-protein ligase SH3RF2 (IPR028511)

Short name: SH3RF2

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Plenty of SH3 domains protein 2 (POSH2 also known as SH3 domain-containing RING finger protein 3 or putative E3 ubiquitin-protein ligase SH3RF2) contains the Src homology 3 (SH3) domains and a RING finger domain which confers E3 ligase activity to the protein. It belongs to the POSH family, which includes POSH1, POSH2 and POSH3 [PMID: 20696164]. POSH2 interacts with GTP-loaded Rac1, which is a small signaling G protein [PMID: 20696164].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER