Family

c-Cbl associated protein (IPR028506)

Short name: CAP/ponsin

Family relationships

None.

Description

c-Cbl associated protein (also known as CAP or ponsin) belongs to a family of adaptor protein containing two other members, ArgBP2 and Vinexin [PMID: 11937713]. It has an N-terminal sorbin homology (SoHo) domain and three C-terminal SH3 domain (Src homology domain 3) [PMID: 11937713]. It has been implicated in the insulin signalling and is required for insulin-stimulated glucose transport [PMID: 11001060]. CAP binds to the major endocytic factor dynamin and affects the actin cytoskeleton organisation [PMID: 19116150].

GO terms

Biological Process

GO:0007015 actin filament organization
GO:0008286 insulin receptor signaling pathway

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER