Protein S100-B (IPR028481)

Short name: S100-B

Overlapping homologous superfamilies

Family relationships



S100-B belongs to the S100 calcium-binding family. It has been implicated in oligodendrocyte progenitor cell (OPC) regeneration in response to demyelinating insult [PMID: 15555923, PMID: 20351179]. S100B is a marker of the glial cells and its expression defines a late developmental stage after which GFAP-expressing cells lose their neural stem cell potential [PMID: 17078026]. S100-B can be used as a marker for early assessment of minor head injury and blood-brain barrier disruption [PMID: 21944878, PMID: 18221201].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005509 calcium ion binding
GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.