Family

Twinfilin (IPR028458)

Short name: Twinfilin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents the twinfilin family. Its members include twinfilin from Drosophila and twinfilin-1/2 from mammals. They are actin-binding proteins involved in motile and morphological processes [PMID: 11724820, PMID: 16511569]. They inhibit actin polymerisation, likely by sequestering G-actin [PMID: 16511569].

GO terms

Biological Process

GO:0030837 negative regulation of actin filament polymerization

Molecular Function

GO:0003779 actin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER