Plakophilin-4 (IPR028443)

Short name: Plakophilin-4

Overlapping homologous superfamilies


Family relationships


Plakophilin-4 (protein p0071) is the most distantly related of the plakophilins [PMID: 15819401]. Protein p0071 plays a role as a regulator of Rho activity during cytokinesis [PMID: 17115030]. It is absent from desmosomes [PMID: 19005682] and it is a major constituent of the myocardial composite junctions and of the diverse morphological forms of adherens junctions in which it forms stable complexes with specific catenins and 'classic' cadherins [PMID: 19092057].

GO terms

Biological Process

GO:0007155 cell adhesion
GO:0043547 positive regulation of GTPase activity
GO:0032467 positive regulation of cytokinesis

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.