Transcription factor GATA-6 (IPR028437)

Short name: TF_GATA_6

Family relationships


Members of the GATA family of zinc finger transcription factors regulate critical steps of cellular differentiation during vertebrate development. GATA-6 has been implicated in the regulation of myocardial differentiation during cardiogenesis [PMID: 10608869]. Mutations in GATA-6 have been implicated as genetic causes of congenital heart diseases involving cardiac outflow tract defects [PMID: 19666519].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 sequence-specific DNA binding transcription factor activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.