Huntingtin family (IPR028426)

Short name: Huntingtin_fam

Family relationships

  • Huntingtin family (IPR028426)


The huntingtin family consists of huntingtin proteins, including Dictyostelium HD protein homologue. Abnormalities in the huntingtin protein (Htt) are associated with Huntington's disease [PMID: 22932724], but despite its importance the function of Htt is largely unknown. In Dictyostelium discoideum Htt is required for normal chemotaxis and cytokinesis [PMID: 21562226].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.