Suppressor of cytokine signalling 7 (IPR028423)

Short name: SOCS7

Family relationships



SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation [PMID: 16127460]. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [PMID: 15677474].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.