Retinoblastoma-like protein 1 (IPR028310)

Short name: RBL1

Overlapping homologous superfamilies


Family relationships


This entry represents the retinoblastoma-like protein 1 (RBL1, also known as p107). Members of this family contain a conserved domain named the 'pocket' that interacts with the LXCXE motif found in viral proteins, such as SV40 large T antigen [PMID: 17854503]. RBL1 is a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [PMID: 17531812, PMID: 17671431].

GO terms

Biological Process

GO:0007049 cell cycle

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005667 transcription factor complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.