Family

Centrosomal protein of 126kDa (IPR028257)

Short name: CEP126

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Centrosomal protein of ~126kDa (CEP126), previously known as KIAA1377 [PMID: 22264561], localises to the centrosome, pericentriolar satellites and the base of the primary cilium. It is an important regulator of centrosomal function. Cep126 is necessary for microtubule (MT) organisation, association of the MT array with the centrosome, and is also required for the formation of the primary cilium [PMID: 24867236].

GO terms

Biological Process

GO:0031122 cytoplasmic microtubule organization
GO:0007052 mitotic spindle organization
GO:1905515 non-motile cilium assembly

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005813 centrosome
GO:0097546 ciliary base

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER