Family

Transcription cofactor vestigial-like protein 4 (IPR028184)

Short name: VGLL4

Family relationships

None.

Description

Transcription cofactor vestigial-like protein 4 (Vgl-4) is a member of the Vgl family of TEF-1 (transcriptional enhancer factor-1) cofactors. Vgl-4 has two TDU motifs and is the only Vgl member expressed in the heart [PMID: 15140898]. Vgl-4 modulates the activity of TEF-1 factors and counteracts alpha1-adrenergic activation of gene expression in cardiac myocytes [PMID: 15140898].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam