Domain

Transcriptional regulator (IPR028141)

Short name: Transcriptional_reg_dom

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents a domain found in some transcriptional regulatory proteins of the two-component systems (usually consist of a histidine protein kinase and a response regulator protein) from bacteria. The family is found in association with IPR001789. Proteins containing this domain include DpiA from E. coli , CitT from Bacillus subtilis and CitB from Klebsiella pneumoniae. DpiA is a member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance [PMID: 19202292]. CitT is a member of the two-component regulatory system CitT/CitS [PMID: 11717295], while CitB is a member of the two-component regulatory system CitA/CitB essential for expression of citrate-specific fermentation genes [PMID: 10447894].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam