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Overview
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Domain architectures
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Structures
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Cross-references
Dermcidin (IPR028130)
Short name: Dermcidin
Overlapping homologous superfamilies
None.
Family relationships
None.
Description
Dermcidin is an antibiotic peptide secreted by sweat glands. It is proteolytically processed to generate a 47-amino acid peptide with antimicrobial activity in response to a variety of pathogenic microorganisms [PMID: 11694882, PMID: 15561843, PMID: 22884922].
GO terms
Biological Process
GO:0031640 killing of cells of other organism
Molecular Function
GO:0008233 peptidase activity
Cellular Component
GO:0005576 extracellular region
Contributing signatures
- PTHR40711:SF1 (PTHR40711:SF1)
- PF15291 (Dermcidin)