Chibby family (IPR028118)

Short name: Chibby_fam

Family relationships


This family from eukaryotes includes the chibby proteins and spermatid-associated protein (Spert). Chibby proteins inhibit the wingless/Wnt pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation. Chibby is Japanese for small, and is named after the RNAi phenotype seen in Drosophila [PMID: 12712206]. Spermatid-associated protein is expressed in the flower-like structure in spermatids and its function is unclear [PMID: 12204287].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.