G6B family (IPR028070)

Short name: G6B

Overlapping homologous superfamilies


Family relationships



Protein G6b is expressed in platelets and inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. It appears to operate in a calcium-independent manner [PMID: 17311996]. The human G6B gene encodes a number of splice forms that are translated into both cell-surface and secreted isoforms. Cell-surface isoforms G6B-A and G6B-B have the same extracellular N-terminal Ig-like domain but differ in their C-terminal cytoplasmic tails.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.