InterPro-
Overview
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Structures
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Cross-references
G6B family (IPR028070)
Short name: G6B
Overlapping homologous superfamilies
None.
Family relationships
None.
Description
Protein G6b is expressed in platelets and inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. It appears to operate in a calcium-independent manner [PMID: 17311996]. The human G6B gene encodes a number of splice forms that are translated into both cell-surface and secreted isoforms. Cell-surface isoforms G6B-A and G6B-B have the same extracellular N-terminal Ig-like domain but differ in their C-terminal cytoplasmic tails.
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
No terms assigned in this category.
Cellular Component
GO:0016021 integral component of membrane
