Domain

Domain of unknown function DUF4460 (IPR028031)

Short name: DUF4460

Domain relationships

None.

Description

This domain of unknown function has a conserved HPD sequence motif. There are two completely conserved residues (N and F) that may be functionally important. The domain is found in eukaryotic proteins, including T-cell activation inhibitor which may have a role in regulation of T cell activation or apoptosis [PMID: 17456197, PMID: 19684086].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam