Family

Interleukin-31 (IPR027987)

Short name: IL-31

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents interleukin 31 (IL-31), it is a four-helix bundle cytokine that is preferentially produced by T helper type 2 cells [PMID: 15184896, PMID: 17030248]. It is associated with pruritus, a characteristic feature of atopic dermatitis [PMID: 22621183], and with other types of allergic contact dermatitis-provoked skin inflammation [PMID: 17030248].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER