Family

Pre-T-cell antigen receptor (IPR027834)

Short name: PTCRA

Family relationships

None.

Description

The pre-T-cell antigen receptor (pre-TCR), expressed by immature thymocytes, has a pivotal role in early T-cell development, including TCR beta-selection, survival and proliferation of CD4(-)CD8(-) double-negative thymocytes, and subsequent alpha/beta T-cell lineage differentiation [PMID: 20944746]. This protein contains an immunoglobulin domain [PMID: 20944746].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER