CASTOR, ACT domain (IPR027795)

Short name: CASTOR_ACT_dom

Overlapping homologous superfamilies


Domain relationships



The ACT domain is a structural motif of 70-90 amino acids that functions in the control of metabolism, solute transport and signal transduction. They are thus found in a variety of different proteins in a variety of different arrangements [PMID: 16987805]. In mammalian phenylalanine hydroxylase the domain forms no contacts but promotes an allosteric effect despite the apparent lack of ligand binding [PMID: 18368466].

This ACT domain is found in CASTOR proteins IPR026249 and C-terminal in some aspartate kinases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.