Dynactin subunit 6 (IPR027777)

Short name: DCTN6

Overlapping homologous superfamilies

Family relationships



Dynactin is a complex that binds to cytoplasmic dynein and is a required activator for cytoplasmic dynein-mediated vesicular transport. Dynactin localises to the cleavage furrow and to the midbodies of dividing cells, suggesting that it may function in cytokinesis [PMID: 9722614, PMID: 23589491]. This entry represents the subunit6 (DCTN6) of the Dynactin complex. DCTN6 is critical for dynein-mediated early endosome movement but not for dynein-mediated nuclear distribution [PMID: 21708978].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005869 dynactin complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.