Microtubule-associated protein 1A/1B light chain 3C (IPR027731)

Short name: MAP1A/MAP1B_LC3C

Overlapping homologous superfamilies

Family relationships


Autophagy-related protein LC3C (also known as microtubule-associated proteins 1A/1B light chain 3C) is a member of the ATG8 family, LC3 subfamily [PMID: 12740394]. It is an ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 [PMID: 22470510]. LC3C recruites all ATG8 family members to infecting bacteria such as Salmonella typhimurium [PMID: 23022382].

GO terms

Biological Process

GO:0006914 autophagy

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.