Troponin T (IPR027707)

Short name: TNNT

Overlapping homologous superfamilies


Family relationships


The troponin (Tn) complex regulates calcium-induced muscle contraction. Tn contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT), which is required for Ca(2+)-mediated activation of actomyosin ATPase activity [PMID: 20965144, PMID: 16839517]. Three different troponin T genes that encode tissue-specific isoforms of subunit T have been found in mammals and birds, encoding cardiac (TNNT2), slow (TNNT1), and fast (TNNT3) skeletal muscle TnT isoforms [PMID: 2993302, PMID: 1433301, PMID: 9689598, PMID: 10095098].

GO terms

Biological Process

GO:0006937 regulation of muscle contraction

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005861 troponin complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.