Family

Flotillin family (IPR027705)

Short name: Flotillin_fam

Family relationships

None.

Description

Proteins in this entry include flotillin-1 (also known as reggie-2), flotillin-2 (also known as reggie-1) and their homologues. Flotillin-1 and flotillin-2 associate with membrane microdomains known as rafts [PMID: 11598189]. They play a role in various cellular processes such as insulin signaling, T cell activation, membrane trafficking, phagocytosis, and epidermal growth factor receptor signaling [PMID: 17482313].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER