Neurofilament medium polypeptide (IPR027697)

Short name: NF-M

Overlapping homologous superfamilies


Family relationships


Neurofilament triplet proteins, NF-L, NF-M, and NF-H (light, medium, and heavy), are type IV intermediate filament proteins [PMID: 17498690]. They are essential for the radial growth of axons during development, the maintenance of axon caliber and the transmission of electrical impulses along axons [PMID: 22956720].

This entry represents the NF-M subunit.

GO terms

Biological Process

GO:0061564 axon development

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005883 neurofilament

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.