Family

Eukaryotic translation initiation factor 3 subunit A (IPR027512)

Short name: EIF3A

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Eukaryotic translation initiation factor 3 subunit A is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. However, the subunit is not required for the general function of eIF3 in translation initiation [PMID: 20647036]. It may play a role in regulating translation of a subset of mRNAs and in regulating cell cycle progression and cell proliferation [PMID: 19327350].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005852 eukaryotic translation initiation factor 3 complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP