Lon protease homologue, chloroplastic/mitochondrial (IPR027503)

Short name: Lonm_euk

Overlapping homologous superfamilies


Family relationships


Lon protease is an ATP-dependent serine proteases that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins [PMID: 17216028]. Proteins in this entry are the eukaryotic homologues of the Lon protease that localise at the mitochondrial matrix. They may also have a chaperone function in the assembly of inner membrane protein complexes. They may participate in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome [PMID: 12198491]. In plants, they also localise at the chloroplast [PMID: 17478548].

GO terms

Biological Process

GO:0006515 protein quality control for misfolded or incompletely synthesized proteins

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.