DNA polymerase beta, N-terminal domain (IPR027420)

Short name: PolB_N

Domain relationships


This domain is found at the N terminus of DNA polymerase beta (pol beta) and crossover junction endonuclease MUS81. It corresponds to the lyase domain of pol beta which is responsible for most of its DNA binding activity. This domain also contains the important dRP lyase catalytic activity of the enzyme [PMID: 9556598, PMID: 9657672].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.