Homologous Superfamily

PNPase/RNase PH domain superfamily (IPR027408)

Short name: PNPase/RNase_PH_dom_sf

Description

Polynucleotide phosphorylase (PNPase) is a polyribonucleotide nucleotidyl transferase EC:2.7.7.8 that degrades mRNA in prokaryotes. Polynucleotide phosphorylase and the Ribonuclease PH (RNase PH) family possess a common domain represented by this entry. This suggests similar structures and mechanisms of action for these 3'-->5' phosphorolytic enzymes [PMID: 9241229]. In the case of PNPase, the core domain is found duplicated [PMID: 11080643].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D