Coronin 2B (IPR027339)

Short name: CORO2B

Overlapping homologous superfamilies

Family relationships

  • Coronin (IPR015505)
    • Coronin 2B (IPR027339)


Coronins belongs to the WD40-repeat family, which contains the WD40 motifs that act as the protein-protein interaction sites. There are several isoforms of Coronin in mammalian cells [PMID: 10461187].

This entry represents Coronin 2B (also known as ClipinC). It is predominantly expressed in the brain [PMID: 10224093]. It is a component part of the cross-bridge between the actin cytoskeleton and the plasma membrane. Coronin 2B may play specific roles in the reorganisation of neuronal actin structure [PMID: 10224093].

GO terms

Biological Process

GO:0030036 actin cytoskeleton organization

Molecular Function

GO:0051015 actin filament binding

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.