Family

Coronin 7 (IPR027331)

Short name: CORO7

Overlapping homologous superfamilies

None.

Family relationships

  • Coronin (IPR015505)
    • Coronin 7 (IPR027331)

Description

Coronins belong to the WD40-repeat family, which contains the WD40 motifs that act as the protein-protein interaction sites. There are several isoforms of Coronin in mammalian cells [PMID: 10461187].

This entry represents Coronin 7. Unlike most of the Coronin isoforms, Coronin 7 has not been shown to interact with actin [PMID: 15892111]. Instead, Coronin 7 binds to the outer side of Golgi complex membranes and acts as a mediator of cargo vesicle formation at the trans-Golgi network [PMID: 18925375]. It physically interacts with both the AP-1 adaptor protein complex and the Src kinase [PMID: 18925375].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005794 Golgi apparatus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER