Domain

Quinoprotein alcohol dehydrogenase-like domain (IPR027295)

Short name: Quinoprotein_ADH-like_fam

Domain relationships

Description

Quinoprotein alcohol dehydrogenases are a family of proteins found in methylotrophic or autotrophic bacteria. These quinoproteins use pyrroloquinoline quinone as their prosthetic group. There are three types of alcohol dehydrogenases: type I includes methanol dehydrogenase and ethanol dehydrogenase, type II includes soluble quinohaemoprotein with a C-terminal containing haem C, and type III includes quinoprotein alcohol dehydrogenase with a C-terminal cytochrome C domain [PMID: 11761326]. These quinoproteins contain an 8-bladed beta-propeller motif, which is present in the N-terminal domain of quinoprotein alcohol dehydrogenase, ethanol dehydrogenase, and the heavy chain (alpha subunit) of methanol dehydrogenase (EC:1.1.99.8) [PMID: 11714714, PMID: 12686116, PMID: 12686102]. This entry represents a quinoprotein alcohol dehydrogenase-like domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D