DNA-directed DNA/RNA polymerase mu (IPR027249)

Short name: DNA/RNApol_mu

Overlapping homologous superfamilies


Family relationships


DNA-directed DNA/RNA polymerase mu is a gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ) [PMID: 12640116, PMID: 17483519, PMID: 17915942]. It participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination [PMID: 12932354].

GO terms

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003887 DNA-directed DNA polymerase activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.