Protein phosphatase Slingshot homologue 1 (IPR027233)

Short name: SSH1

Overlapping homologous superfamilies


Family relationships


Slingshot homologue 1 (SSH1) is a protein phosphatase which regulates actin filament dynamics. It dephosphorylates and activates the actin binding/depolymerising factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly [PMID: 14531860, PMID: 15660133, PMID: 16230460].

GO terms

Biological Process

GO:0030036 actin cytoskeleton organization

Molecular Function

GO:0016791 phosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.