Transcriptional activator NFYC/HAP5 subunit (IPR027170)

Short name: NFYC/HAP5_su

Overlapping homologous superfamilies


Family relationships



NFYC/HAP5 is a subunit of the HAP complex that recognises and binds the CCAAT motif in promoters [PMID: 7828851], which stimulates the transcription of various genes [PMID: 12401788]. In mammals and plants, HAP complex includes three subunits: NF-YA (CBF-B or HAP2), NF-YB (CBF-A or HAP3), and NF-YC (CBF-C or HAP5) [PMID: 10571030]. In budding yeast, HAP complex is composed of four subunits: HAP2, HAP3, HAP4, and HAP5 [PMID: 16278450].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 DNA binding transcription factor activity

Cellular Component

GO:0016602 CCAAT-binding factor complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.