TNF receptor-associated factor 5 (IPR027130)

Short name: TRAF5

Family relationships


TNF receptor-associated factor 5 (TRAF5) is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. TRAF5 mediates activation of NF-kappa-B and probably JNK [PMID: 8663299, PMID: 8790348, PMID: 10449775, PMID: 17633015].

GO terms

Biological Process

GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0007165 signal transduction

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.